Anxiolytic Action of Taurine via Intranasal Administration in Mice
نویسندگان
چکیده
منابع مشابه
Immunotherapy of Chenopodium Album Induced Asthma by Intranasal Administration of CpG Oligodeoxynucleotides in BALB/c Mice
Background: There are many therapeutic methods for allergic conditions. CpG oli-gonucleotides play a critical role in immunity via the augmentation of Th1 and suppres-sion of Th2 responses. Objective: In the present study we aimed to estimate the effec-tiveness of intranasal administration of CpG ODN plus Chenopodium album allergen in allergic asthma compared with the administration of allergen...
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Intranasal administration is a method of delivering therapeutic agents to the central nervous system (CNS). It is non-invasive and allows large molecules that do not cross the blood-brain barrier access to the CNS. Drugs are directly targeted to the CNS with intranasal delivery, reducing systemic exposure and thus unwanted systemic side effects. Delivery from the nose to the CNS occurs within m...
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Bacteriophages (phages) are ubiquitous viruses that control the growth and diversity of bacteria. Although they have no tropism to mammalian cells, accumulated evidence suggests that phages are not neutral to the mammalian macro-host and can promote immunomodulatory and anti-tumorigenic activities. Here we demonstrate that Ff phages that do not display any proteins or peptides could inhibit the...
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Putative activity of hydroalcoholic and aqueous infusion extracts of Echium amoenum L. was investigated in mice using the rotarod model of motor coordination and the elevated plus maze model of anxiety. The extracts were administered intraperitonealy (i.p.) once, one hour before performing the tests. Preliminary phytochemical study of the plant, with standard procedures, showed that it contains...
متن کاملIntranasal administration of drugs.
OBJECTIVE To investigate how nasally applied substances distribute in the nose depending on the form of application. DESIGN Observer-blinded study. SETTING University hospital research unit. PARTICIPANTS Fifteen healthy volunteers aged 22 to 32 years. INTERVENTIONS Forms of application included (1) nasal drops applied with a pipette, (2) nasal spray, and (3) a system producing squirts. ...
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ژورنال
عنوان ژورنال: Biomolecules & Therapeutics
سال: 2019
ISSN: 1976-9148,2005-4483
DOI: 10.4062/biomolther.2018.218